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ACLS practice test, ACLS pretest questions, ACLS practice questions and the 2025 ACLS algorithms

Almost every free ACLS practice test online is a recycled pool of questions written against the 2020 Guidelines, and a good number of them are scraped from someone's course handout. That matters more than usual right now, because the science changed in October 2025 and the courses changed with it. Before you answer a single practice question, be clear about which of the two ACLS tests you are actually preparing for, because they have different passing scores, different formats and different consequences for failing.

  • Unlimited ACLS practice questions across rhythm recognition, pharmacology and the 2025 Guidelines algorithms
  • Written to both gates: the 70% precourse self-assessment and the 84% ACLS provider exam
  • Every answer choice explained, including the dose, the timing and why the plausible wrong ones fail
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The short answer

There are two separate ACLS tests, and most candidates only prepare for one of them. The AHA Precourse Self-Assessment is mandatory before you may take an ACLS course, is scored at 70% to pass, may be retaken as many times as you need, and covers three sections: rhythm recognition, pharmacology and practical application. The ACLS Provider written exam at the end of the course is 50 multiple-choice questions with a passing score of 84%, and it is open resource, so you may use the provider manual, handouts and your own notes while you sit it. Both now test the 2025 AHA Guidelines for CPR and ECC, published October 22, 2025, which every AHA Training Center has been required to teach since March 1, 2026. An ACLS provider card is valid for two years.

Last updated August 2026

Work the questions

ACLS practice test questions with answers and explanations

Eight questions in the style of the ACLS Provider exam and the precourse self-assessment, spread across rhythm recognition, pharmacology and practical application. They are written to the published course content rather than copied from any secure exam.

Question 1 · Cardiac arrest: shockable rhythms

Which rhythms in cardiac arrest are shockable?

  1. A. Ventricular fibrillation and asystole
  2. B. Ventricular fibrillation and pulseless ventricular tachycardia
  3. C. Pulseless electrical activity and asystole
  4. D. Pulseless electrical activity and pulseless ventricular tachycardia
Show the answer and explanation

B. Ventricular fibrillation and pulseless ventricular tachycardia

There are exactly two shockable rhythms in cardiac arrest, and knowing that as a closed set answers a large share of rhythm questions by elimination. Defibrillation works by depolarizing enough myocardium at once to let the natural pacemaker resume, which requires disorganized electrical activity to interrupt. Asystole has no electrical activity to reorganize, so shocking it accomplishes nothing. PEA is organized electrical activity that is failing to produce mechanical output, so the problem is not the rhythm and the answer is compressions, epinephrine and a hunt for the reversible cause. PEA is defined as any organized rhythm without a pulse that is not VF or pVT.

Question 2 · Pharmacology: refractory VF

A patient in ventricular fibrillation remains in VF after defibrillation, CPR and a first dose of epinephrine. Which antiarrhythmic and dose is indicated?

  1. A. Amiodarone 150 mg, then 300 mg for the second dose
  2. B. Amiodarone 300 mg, then 150 mg for the second dose
  3. C. Atropine 1 mg, repeated every 3 to 5 minutes
  4. D. Adenosine 6 mg, then 12 mg for the second dose
Show the answer and explanation

B. Amiodarone 300 mg, then 150 mg for the second dose

Amiodarone in cardiac arrest goes high then low: 300 mg for the first dose and 150 mg for the second. The reversed order in option A is the single most common distractor on this item, so fix the direction rather than the numbers. Lidocaine is an accepted alternative to amiodarone here. Atropine belongs to symptomatic bradycardia in a patient who has a pulse and has no role in cardiac arrest. Adenosine belongs to stable narrow-complex tachycardia, also in a patient with a pulse. Both wrong options are correct drugs attached to the wrong branch of the algorithm, which is exactly how ACLS pharmacology questions are usually built.

Question 3 · Practical application: tachycardia

A patient has a heart rate of 180, a systolic blood pressure of 76 and is confused and difficult to rouse. What is the immediate treatment?

  1. A. Obtain a 12-lead ECG and seek expert consultation
  2. B. Give adenosine 6 mg rapid IV push
  3. C. Perform immediate synchronized cardioversion
  4. D. Begin chest compressions
Show the answer and explanation

C. Perform immediate synchronized cardioversion

The whole tachycardia algorithm turns on one judgment: stable or unstable. Unstable means poor blood pressure and poor mentation, and this patient has both, so the answer is electricity now rather than a drug. Option A is the correct action for a stable patient, where you do have time for a 12-lead and consultation, and it is the trap for candidates who read the rate rather than the perfusion. Adenosine is for stable narrow-complex tachycardia. Compressions are wrong because the patient has a pulse, and starting them on a perfusing rhythm is a harm. Note the word synchronized: cardioversion in a patient with a pulse is timed to the R wave, and an unsynchronized shock risks inducing VF.

Question 4 · Rhythm recognition: heart block

A rhythm strip shows regular P waves and regular QRS complexes at different rates, with no consistent relationship between them. This is:

  1. A. First degree AV block
  2. B. Second degree AV block, type 1
  3. C. Second degree AV block, type 2
  4. D. Third degree AV block
Show the answer and explanation

D. Third degree AV block

Third degree block is complete dissociation: the atria and ventricles each march along at their own regular rate and ignore each other entirely, so no PR interval can be measured because no P wave is conducting. That description of two independent regular rhythms is the giveaway. First degree block conducts every beat with a uniformly prolonged PR interval. Type 1 second degree block shows the PR interval lengthening progressively until a beat is dropped, then resetting. Type 2 drops beats without warning while the conducted beats keep a fixed PR interval. Learn these four as a sequence of worsening conduction and the distinctions become one idea rather than four facts.

Question 5 · Practical application: capnography

During CPR on an intubated patient, the end-tidal CO2 waveform reads 6 mmHg. What does this most likely indicate?

  1. A. The endotracheal tube has become dislodged
  2. B. Chest compressions are not effective
  3. C. Return of spontaneous circulation has occurred
  4. D. The patient is being ventilated too slowly
Show the answer and explanation

B. Chest compressions are not effective

A persistent end-tidal CO2 under 10 mmHg in an intubated patient receiving CPR indicates poor compression quality, because exhaled CO2 depends on pulmonary blood flow and during arrest that flow is entirely generated by the compressor. The correct response is to fix the compressions: check depth, check rate, allow full recoil, and change the compressor. A dislodged tube typically produces an abrupt loss of waveform rather than a low but present reading. ROSC classically causes a sudden rise in end-tidal CO2, not a fall, and that abrupt jump is one of the earliest signals you will get. This is why waveform capnography does two jobs at once: it is the most reliable confirmation of tube placement and a continuous measure of how well the resuscitation is going.

Question 6 · Post-cardiac arrest care

After return of spontaneous circulation, a patient is unable to follow commands. Which intervention is indicated?

  1. A. Targeted temperature management at 32 to 36 degrees Celsius for at least 24 hours
  2. B. Immediate extubation to assess neurological status
  3. C. Withholding oxygen to avoid hyperoxia
  4. D. Routine administration of a further epinephrine dose
Show the answer and explanation

A. Targeted temperature management at 32 to 36 degrees Celsius for at least 24 hours

The trigger for targeted temperature management is the patient who does not follow commands after ROSC, and that condition is the part candidates drop when they memorize the intervention without the indication. The post-arrest sequence runs in order: optimize ventilation and oxygenation, treat hypotension where systolic pressure is under 90 mmHg, go to the cath lab if there is a STEMI, and start temperature management if the patient cannot follow commands. Extubating a patient who cannot follow commands to test neurology is unsafe. Oxygenation is optimized rather than withheld, titrated to avoid both hypoxia and unnecessary hyperoxia. Epinephrine belongs to the arrest itself and is not continued routinely after circulation returns.

Question 7 · Practical application: high-performance teams

A team leader orders amiodarone during a resuscitation and the team member responds by administering the drug without speaking. Which element of effective team dynamics is missing?

  1. A. Mutual respect
  2. B. Closed-loop communication
  3. C. Clear roles and responsibilities
  4. D. Knowing your limitations
Show the answer and explanation

B. Closed-loop communication

Closed-loop communication means the order is repeated back to the person who gave it and its completion is reported, so the leader knows the drug was heard correctly, is being given, and has actually gone in. Silently doing the right thing breaks the loop, because the leader now has to guess, and in a code the guess is often wrong about the dose or the timing. This is also where an incorrect dose gets caught, since repeating it back exposes the error before it reaches the patient. The other options name real behaviors in the AHA list but describe different failures: clear roles is about task assignment at the start, knowing your limitations is about asking for a different role, and mutual respect is about tone. The Megacode assesses these explicitly, which is why saying the algorithm out loud is a skill worth rehearsing.

Question 8 · Practical application: stroke

A patient arrives with suspected acute ischemic stroke. Within what time frame should a noncontrast head CT be obtained?

  1. A. Within 20 minutes of hospital arrival
  2. B. Within 60 minutes of hospital arrival
  3. C. Within 90 minutes of hospital arrival
  4. D. Within 3 hours of symptom onset
Show the answer and explanation

A. Within 20 minutes of hospital arrival

Twenty minutes from arrival, and the reason is the fork it opens. Fibrinolytic therapy is the treatment for ischemic stroke and is actively dangerous in hemorrhagic stroke, so nothing can proceed until imaging distinguishes them, and every minute spent waiting for the scan is a minute of the treatment window burned. The 90-minute figure in option C is the door-to-balloon target for percutaneous coronary intervention in STEMI, a different pathway that candidates routinely swap in here. Do not confuse the imaging deadline with the treatment window either: three hours refers to eligibility for fibrinolysis from symptom onset, which is a separate clock that started before the patient reached you.

These eight are a sample. Inside Aspirants.ai you can generate unlimited ACLS practice questions across rhythm recognition, pharmacology and the 2025 Guidelines algorithms, with the reasoning behind every answer choice rather than a bare answer key.

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What is the ACLS pretest, and how is it different from the ACLS exam?

These are two different tests taken weeks apart, and confusing them is the most common preparation mistake in ACLS. The first is the Precourse Self-Assessment, which the AHA requires you to complete before you are allowed to attend an ACLS course at all. It is an online assessment delivered through the AHA eLearning platform, it is scored, and you need at least 70% to pass. There is no limit on attempts, so you take it until you clear it, then print the certificate of completion and bring it to class or send it to your training center in advance. It covers three defined sections: rhythm recognition, pharmacology, and practical application. One genuinely useful change arrived with the 2025 Guidelines: the AHA made the ACLS Precourse Self-Assessment free and open to everyone, so you can now work through it as a study tool whether or not you have booked a course. The second test is the ACLS Provider written exam, sat at the end of the course. That one is 50 multiple-choice questions and the passing score is 84%, which on 50 questions means you can miss eight and pass, and missing nine fails you. It is an open-resource exam. Neither of these is the part that actually fails people, though. The Megacode is the in-person skills test where you lead a simulated resuscitation, and it is judged on performance rather than a percentage.

What is the passing score for ACLS?

Eighty-four percent on the ACLS Provider written exam, and 70% on the Precourse Self-Assessment. Those two numbers are not interchangeable and it is worth fixing them separately in your head, because the tighter one comes second. On a 50-question exam, 84% is 42 correct. You have eight wrong answers of margin, not fifteen. That is a narrow band for a test that spans rhythm interpretation, drug doses, defibrillation energy, airway management and post-arrest care, and it is the reason the open-resource rule exists rather than being a generosity. All AHA exams are now open resource, meaning you may use the ACLS Provider Manual, the course handouts and your personal notes during the written exam. Read that as a signal about what the exam is testing. An open-resource exam cannot reward memorization, so it stops asking what the dose of amiodarone is and starts asking which drug this patient needs, in what sequence, and at what point in the algorithm. Candidates who prepare by making a flashcard deck of doses and then discover they may bring the manual anyway have usually prepared for the wrong exam. Build the reference you will actually use instead: a single page with the cardiac arrest, bradycardia and tachycardia algorithms and the doses attached to each branch, tabbed so you can find it in ten seconds under time pressure.

The 2025 AHA Guidelines changed ACLS, and a lot of practice material has not caught up

The 2025 American Heart Association Guidelines for CPR and Emergency Cardiovascular Care were published in Circulation on October 22, 2025, and the AHA launched updated BLS, ACLS and PALS courses the same day. The deadline that matters to you has already passed: since March 1, 2026, every AHA Training Center and instructor has been required to teach from the updated materials. If you are sitting an ACLS course now, you are sitting the 2025 course, and any practice question written against the 2020 Guidelines is testing a syllabus that is no longer current. Several changes are worth knowing by name. The AHA replaced the separate adult and pediatric, in-hospital and out-of-hospital chains with a single unified Chain of Survival, so there is now one model rather than four. The adult choking sequence is stated as cycles of 5 back blows followed by 5 abdominal thrusts, continued until the obstruction is relieved or the patient becomes unresponsive. Naloxone now appears explicitly in the algorithm for suspected opioid overdose in respiratory or cardiac arrest, which reflects how much of the out-of-hospital arrest population that now describes. And the guidelines add a recommendation for safety huddles on high-risk hospitalized patients, on the evidence that improving team awareness of a deteriorating patient prevents arrests rather than treating them. The core resuscitation mechanics did not change: compressions at least 2 inches deep at 100 to 120 per minute, interruptions under 10 seconds, and a compressor change every 2 minutes.

The ACLS algorithms are the exam, so learn them as decisions rather than diagrams

Most of what the ACLS written exam and the Megacode ask you is a variation on one question: given this rhythm and this patient, what do you do next. That is why memorizing the algorithm posters as pictures does not survive contact with a scenario. Learn them as a small number of decisions instead. In cardiac arrest, the first fork is whether the rhythm is shockable. Only two rhythms in cardiac arrest are: ventricular fibrillation and pulseless ventricular tachycardia. Everything else is asystole or PEA, where PEA is defined as any organized rhythm without a pulse that is not VF or pVT. That single definition answers a surprising share of rhythm questions. On the shockable branch you shock, resume compressions immediately, give epinephrine 1 mg every 3 to 5 minutes, and add amiodarone at 300 mg for the first dose and 150 mg for the second, with lidocaine as the alternative. On the non-shockable branch you give epinephrine 1 mg every 3 to 5 minutes and hunt reversible causes. For a patient with a pulse the fork is different and simpler: stable or unstable. Unstable means poor blood pressure and poor mentation, and it moves you to electricity. Unstable tachycardia gets immediate synchronized cardioversion. Symptomatic bradycardia gets atropine 1 mg every 3 to 5 minutes to a maximum total of 3 mg, then pacing or an infusion if atropine fails. Stable means you have time, so you get a 12-lead and expert consultation, and stable narrow-complex tachycardia gets adenosine, 6 mg first and 12 mg second.

Rhythm recognition is where candidates quietly lose the most marks

One of the three sections of the Precourse Self-Assessment is rhythm recognition, and it is the section people fail. The reason is that reading a rhythm strip is a pattern skill built by volume, not a fact you can revise the night before. The list you are responsible for is finite and short, which is the good news. On the tachycardia side: sinus tachycardia, atrial fibrillation, atrial flutter, supraventricular tachycardia, monomorphic ventricular tachycardia and polymorphic ventricular tachycardia. On the bradycardia side: sinus bradycardia, first degree heart block, second degree heart block type 1, second degree type 2, and third degree block. In cardiac arrest: ventricular fibrillation, pulseless VT, asystole and PEA. That is roughly fifteen patterns. Work them as pairs that are easy to confuse rather than as a list. Atrial fibrillation against atrial flutter is irregularly irregular with no discernible P waves against the sawtooth pattern with a regular ventricular response. SVT against sinus tachycardia is usually a rate question at the extremes and a P wave question in the middle. Second degree type 1 against type 2 is the PR interval lengthening progressively before a dropped beat, against a fixed PR interval with beats dropped without warning. Third degree is the one where the P waves and the QRS complexes are each regular but have nothing to do with each other. Get those four pairs right and the rest of the list falls out.

How many questions are on the ACLS exam, and how hard is it really?

Fifty multiple-choice questions on the ACLS Provider written exam, with 42 correct required. The honest answer on difficulty is that the written exam is not the hard part for most candidates, and treating it as the hard part is what causes trouble. It is open resource, the question style is direct, and a nurse or paramedic who works the algorithms for a few hours passes it comfortably. What catches people is the Megacode, the in-person skills test where you take the team leader role through a simulated resuscitation and are assessed on whether you actually ran it: whether you assigned roles, whether compressions started fast and stayed deep enough with short interruptions, whether you called for the right drug at the right point, whether you used closed-loop communication, and whether you identified the reversible cause. The AHA describes the effective team behaviors explicitly and they are testable: clear roles and responsibilities, knowing your own limitations, constructive intervention when someone is about to make an error, knowledge sharing, summarizing and re-evaluating, closed-loop communication where the order is repeated back, and mutual respect. The team roles are named too: team leader, compressor, airway, medications, monitor and defibrillator, recorder and timer, and the CPR coach whose specific job is keeping compression quality high. Practice saying the algorithm out loud, as instructions to other people, rather than reading it silently. That is the actual skill being assessed.

Does my employer accept Red Cross ALS instead of AHA ACLS?

Usually yes, and increasingly so, but this is the one question you should confirm with your own employer before you pay for anything. There are two national providers of advanced resuscitation training in the United States. The American Heart Association calls its course Advanced Cardiovascular Life Support, or ACLS. The American Red Cross calls its equivalent Advanced Life Support, or ALS, and states plainly on its own page that ALS is often used interchangeably with the term ACLS, describing its program as scientifically equivalent to and educationally superior to the alternative. Both issue a two-year certification. Both require BLS proficiency as the only hard prerequisite. Both are delivered as classroom or blended learning, where an online course is followed by an in-person skills session with a certified instructor. The differences that matter in practice are structural rather than clinical. Red Cross builds adaptive learning into its online component, so a provider who demonstrates competency can test out of individual sessions and finish faster. It also splits renewal into two named routes: a Recertification Option with a brief in-person skills review before testing, and a Challenge Option that takes an experienced provider straight to the skills test. The AHA equivalent for experienced providers is the separate ACLS for Experienced Providers course, which covers cardiovascular, respiratory and metabolic, and toxicology emergencies plus post-cardiac arrest care. Where employers still specify AHA, it is usually contractual language written years ago rather than a clinical judgment, but it binds you all the same. Ask before you book.

What does the ACLS course actually cover?

The AHA publishes the content list, and it is short enough to use as a study checklist. The ACLS course covers the systematic approach to assessment, high-quality BLS, airway management, rhythm recognition, defibrillation, intravenous and intraosseous access as information only rather than a tested skill, use of medications, cardioversion, transcutaneous pacing, and high-performance teams. Read the IV and IO line carefully, because it settles a common worry: you are not going to be assessed on cannulating anything, so a candidate who is out of practice at access does not need to solve that before the course. What you are assessed on is knowing which drug, when, and by what route. The course is built explicitly on top of BLS rather than repeating it, which is why BLS proficiency is a prerequisite and why compression quality still shows up in the Megacode assessment. Two ACLS course paths exist. The standard ACLS Provider course is written for healthcare professionals who direct or participate in the management of cardiac arrest, stroke and other cardiopulmonary emergencies, which the AHA lists as emergency response, emergency medicine, critical care and intensive care, and surgery personnel, along with anyone who needs the card for a job requirement. ACLS for Experienced Providers is a different course for people already proficient in ACLS skills, ECG interpretation and ACLS pharmacology who regularly lead resuscitations, and it goes deeper into cardiovascular, respiratory, metabolic and toxicology emergencies and post-cardiac arrest care.

ACS, stroke and post-arrest care: the time-bound numbers that get tested

ACLS is not only cardiac arrest, and the sections that are not arrest tend to be tested with a specific number attached, which makes them cheap marks. For acute coronary syndrome, the presentation to know is a pale, cool, diaphoretic patient with chest pain, dyspnea, anxiety, hypotension and poor perfusion. Aspirin is 162 to 325 mg. The reperfusion target is percutaneous coronary intervention within 90 minutes of arrival at the emergency department. For suspected stroke, the number is a noncontrast head CT within 20 minutes of hospital arrival, and the purpose of getting it early is to rule out hemorrhagic stroke, because the treatments diverge completely from that point: ischemic stroke gets fibrinolytic therapy as soon as possible if there are no contraindications, while hemorrhagic stroke gets a neurosurgical consult. Notifying the receiving hospital in advance is part of the answer to a lot of stroke scenario questions, not an optional courtesy. After return of spontaneous circulation, the post-arrest sequence has four steps in order: optimize ventilation and oxygenation, treat hypotension where systolic blood pressure is under 90 mmHg, go to the cath lab if there is a STEMI, and begin targeted temperature management at 32 to 36 degrees Celsius for at least 24 hours if the patient cannot follow commands. That last condition is the one candidates drop. Targeted temperature management is indicated for the patient who does not follow commands after ROSC, not for every resuscitated patient.

Capnography, compression quality and the details that decide a Megacode

A handful of monitoring facts come up repeatedly in both the written exam and the Megacode debrief, and they are the ones that separate a candidate who has memorized an algorithm from one who can run a code. Waveform capnography is the most reliable method of confirming and monitoring endotracheal tube placement, and it does double duty: an end-tidal CO2 under 10 mmHg in an intubated patient indicates that compressions are not effective, so it is a real-time quality measure rather than just an airway check. Compression standard is at least 2 inches deep at 100 to 120 per minute with full recoil between compressions, interruptions kept under 10 seconds, and compressors swapped every 2 minutes because quality falls off measurably before fatigue is felt. Ventilation without an advanced airway runs at 30 compressions to 2 breaths; once an endotracheal tube is in, compressions become continuous and you give one breath every 6 seconds. Rescue breathing for a patient who has a pulse but is not breathing adequately is also one breath every 6 seconds, each delivered gently over 1 second to visible chest rise. Excessive ventilation is a genuine harm rather than a technicality, because it raises intrathoracic pressure and reduces cardiac output. Two defibrillation habits are worth building deliberately: continue compressions while the defibrillator charges, and charge before the rhythm check rather than after it. Pre-charging roughly 15 seconds before a planned rhythm check measurably raises the chest compression fraction, which is the single number most closely tied to survival.

How to use an ACLS practice test without wasting it

Practice questions in ACLS have a specific job, and it is not predicting your score. On the Precourse Self-Assessment you can retake until you pass, so the score is close to meaningless as a target; what the assessment is genuinely good for is telling you which of the three sections is weak. If you clear pharmacology and practical application easily and scrape rhythm recognition, you have learned the most useful thing the test can tell you, and the correct response is a week of strip reading rather than another pass through the drug list. Grade yourself honestly on method, not just outcome. A question you answered correctly by eliminating two options and guessing between the remaining pair is not knowledge, and it will not survive a rephrased item. Mark it wrong in your own review and come back to it. Practice under the constraint you will actually face, which for the written exam means with the manual available. If you never practice with the reference, you will not have built the index you need to use it quickly, and hunting for a dose in a manual you have not tabbed costs more time than the eight-question margin allows. Finally, rehearse out loud. The Megacode assesses whether you can direct a team, and reading an algorithm silently trains a different skill from saying the words in the right order to another person under pressure. Practice questions build the knowledge, but only spoken rehearsal builds the performance the skills test measures.

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The two ACLS tests, side by side

Most candidates prepare for one and are surprised by the other. They have different passing scores, different formats and different rules on retakes.

Precourse Self-Assessment ACLS Provider written exam Megacode
When Before you may attend the course At the end of the course At the end of the course
Format Online, AHA eLearning platform 50 multiple-choice questions In-person simulated resuscitation
Passing standard 70% 84%, which is 42 of 50 Performance assessed by the instructor
Resources allowed Open, it is a self-assessment Open resource: manual, handouts and personal notes None, you lead the team
Retakes Unlimited Set by your training center Remediation and retest at the instructor's discretion
Sections covered Rhythm recognition, pharmacology, practical application Full course content Team leadership and the arrest algorithms

Sources: the AHA ACLS course page at cpr.heart.org and AHA Training Center course documentation, verified August 2026. New with the 2025 Guidelines, the AHA has made the ACLS Precourse Self-Assessment free and open to everyone rather than course enrollees only.

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ACLS drug doses by algorithm branch

The doses the written exam and the Megacode actually ask for, grouped by the decision that leads you to them rather than alphabetically.

Situation Drug Dose Notes
Cardiac arrest, any rhythm Epinephrine 1 mg every 3 to 5 minutes The first drug in both the shockable and non-shockable branches
VF or pulseless VT, refractory to shocks Amiodarone 300 mg first dose, 150 mg second dose Lidocaine may be used instead
Symptomatic bradycardia Atropine 1 mg every 3 to 5 minutes, maximum total 3 mg If atropine fails, move to transcutaneous pacing or an infusion
Stable narrow-complex tachycardia Adenosine 6 mg first dose, 12 mg second dose Unstable tachycardia goes to synchronized cardioversion instead, not adenosine
Suspected acute coronary syndrome Aspirin 162 to 325 mg Target percutaneous coronary intervention within 90 minutes of ED arrival
Suspected opioid overdose in arrest Naloxone Per protocol, alongside standard resuscitation Placed explicitly in the algorithm by the 2025 Guidelines

Doses reflect current ACLS teaching as carried into the 2025 AHA Guidelines courses. This is study material for an exam, not a clinical reference: follow your own institution's protocols and current prescribing information at the bedside.

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AHA ACLS compared with American Red Cross ALS

Two national providers, two names for the same scope of practice. The differences are structural rather than clinical, but employer acceptance is worth confirming before you pay.

AHA ACLS American Red Cross ALS
Course name Advanced Cardiovascular Life Support Advanced Life Support, which the Red Cross states is often used interchangeably with ACLS
Certification validity Two years Two years
Prerequisite BLS skills, the course is built on top of them Proficiency in adult BLS, stated as the only prerequisite
Formats Classroom, or HeartCode blended learning online plus a hands-on skills session Classroom, or blended learning online plus an in-person skills session
Online component HeartCode ACLS, updated to the 2025 Guidelines Adaptive learning with the option to test out of sessions you already know
Renewal route for experienced providers ACLS for Experienced Providers, a separate course covering toxicology and post-arrest care in more depth Recertification Option with a short skills review, or a Challenge Option straight to the skills test
Written exam 50 questions, 84% to pass, open resource Final written exam completed online before the skills session

Sources: cpr.heart.org ACLS course page and redcross.org ALS certification page, both verified August 2026. Employer acceptance of Red Cross ALS is common but not universal, and where AHA is specified it is usually older contractual language rather than a clinical distinction.

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What the 2025 AHA Guidelines changed

Published in Circulation on October 22, 2025. Every AHA Training Center has been required to teach the updated materials since March 1, 2026, so practice questions written to the 2020 Guidelines are now out of date.

Area What changed
Chain of Survival One unified chain replaces the separate adult and pediatric, in-hospital and out-of-hospital chains
Adult choking Stated as cycles of 5 back blows and 5 abdominal thrusts, until relief or the patient becomes unresponsive
Opioid overdose Naloxone appears explicitly in the algorithm for suspected opioid overdose in respiratory or cardiac arrest
Prevention Safety huddles for high-risk hospitalized patients, on evidence that team awareness of deterioration prevents arrests
Precourse Self-Assessment Made free and accessible to everyone rather than restricted to enrolled students
Core CPR mechanics Unchanged: at least 2 inches deep, 100 to 120 per minute, interruptions under 10 seconds, compressor change every 2 minutes

Source: the 2025 AHA Guidelines for CPR and ECC announcement and the AHA ACLS course page. The AHA launched updated BLS, ACLS and PALS courses on the day the guidelines published.

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The ACLS Provider written exam requires 84%, which on a 50-question exam means 42 correct answers and a margin of eight wrong. The separate Precourse Self-Assessment, which you must complete before attending the course, requires 70% and may be retaken as many times as you need.

Fifty multiple-choice questions on the ACLS Provider written exam. All AHA exams are open resource, so you may use the ACLS Provider Manual, course handouts and your own notes while you sit it. The exam is only one of three requirements: you also complete the precourse self-assessment beforehand and the Megacode skills test at the end.

It is the AHA Precourse Self-Assessment, a mandatory online assessment you complete before you are allowed to attend an ACLS course. It covers rhythm recognition, pharmacology and practical application, is scored at 70% to pass, and allows unlimited attempts. Print the certificate of completion and bring it to class. With the 2025 Guidelines the AHA made it free and open to everyone.

Yes. All AHA exams are now open resource, which means the ACLS Provider Manual, study guides, handouts and personal notes may be used during the written exam. That changes what it tests: an open-resource exam asks which drug this patient needs and when, rather than asking you to recall a dose. Practice with the manual so you can actually find things quickly.

Two years. The AHA issues a Provider Course Completion Card valid for two years from completion, and the American Red Cross ALS certificate runs for two years as well. Renewal is either a full course again or, for experienced providers, a shortened route: ACLS for Experienced Providers with the AHA, or the Recertification and Challenge Options with the Red Cross.

Only two: ventricular fibrillation and pulseless ventricular tachycardia. Everything else in cardiac arrest is asystole or pulseless electrical activity, and PEA is defined as any organized rhythm without a pulse that is not VF or pVT. Those two branches drive the whole cardiac arrest algorithm, so learning the shockable pair as a closed set answers a lot of questions by elimination.

One milligram every 3 to 5 minutes, and it is given in both the shockable and non-shockable branches of the cardiac arrest algorithm. Amiodarone is added for VF or pulseless VT that persists after defibrillation, at 300 mg for the first dose and 150 mg for the second, with lidocaine as an accepted alternative.

Partly. Both the AHA and the Red Cross offer blended learning, where you complete the cognitive portion online and then attend an in-person hands-on skills session with a certified instructor. The AHA product is HeartCode ACLS, updated to the 2025 Guidelines. A course that is entirely online with no in-person skills component is not an AHA or Red Cross certification, and employers commonly reject those cards.

For most employers yes, but confirm before you pay. The Red Cross calls its course Advanced Life Support and states that ALS is often used interchangeably with ACLS, describing the training as scientifically equivalent. Both certifications run two years and both require BLS proficiency. Where an employer specifies AHA, it is usually older contractual wording rather than a clinical distinction, but it still binds you.

The 2025 Guidelines published on October 22, 2025 and every AHA Training Center has taught the updated courses since March 1, 2026. Key changes: a single unified Chain of Survival replacing four separate ones, an adult choking sequence of 5 back blows and 5 abdominal thrusts, naloxone placed explicitly in the algorithm for suspected opioid overdose, and safety huddles for high-risk hospitalized patients. Core CPR mechanics did not change.

The Megacode, not the written exam. The written exam is open resource and direct, while the Megacode requires you to lead a simulated resuscitation as team leader: assigning roles, keeping compressions deep and interruptions short, calling the right drug at the right point in the algorithm, using closed-loop communication and identifying the reversible cause. Rehearse the algorithms out loud rather than reading them silently.

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